THE ONLY LONG-LASTING RECOMBINANT FACTOR IX ALBUMIN FUSION PROTEIN

IDELVION keeps FIX in your body longer for an extended half-life, so it can be used when it's needed to control bleeds.

Recombinant albumin is an important
component of IDELVION. Albumin, a
protein that can be found naturally in your
body, is known for its long half-life.

When a bleed occurs, the linker
connecting recombinant albumin and
rFIX in IDELVION is separated, activating
the rFIX to stop the bleeding.

Recombinant Factor IX (rFIX)
is linked to the recombinant
albumin and remains active until
it’s needed to control a bleed.

MOA molecule – Recombinant albumin
  • 1

    Recombinant albumin is an important component of IDELVION. Albumin, a protein that can be found naturally in your body, is known for its long half-life.

  • 2

    When a bleed occurs, the linker connecting recombinant albumin and rFIX in IDELVION is separated, activating the rFIX to stop the bleeding.

  • 3

    Recombinant Factor IX (rFIX) is linked to the recombinant albumin and remains active until it’s needed to control a bleed.

Tony on the science of IDELVION

“What interested me about IDELVION was that it used albumin. From studying biology I knew it was a naturally occurring protein in the body.”

SEE MORE REAL-LIFE STORIES

Extended half-life. Extended time between doses.

HALF-LIFE 104 HOURS

With the longest half-life of any FIX therapy at 104 hours on a single dose,* some people can go up to 2 weeks between doses—while keeping factor levels high to keep them protected.

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What is half-life?

Half-life measures how long it takes for the activity level of your infused factor to drop by 50%. A longer half-life means that the drug is active in your body for a longer time.

*Based on a single dose of IDELVION at 50 IU/kg in adults (≥18 years).

UP TO 14 DAY DOSING FDA APPROVED

See if up to 14-day dosing
is right for you

ZERO SPONTANEOUS BLEEDS

IDELVION delivered a zero median
annualized spontaneous bleeding rate
when dosed at 7 or 14 days in clinical trials

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