IDELVION KEEPS FACTOR IX IN YOUR BODY LONGER

Extended protection. Extended time between doses.

HALF-LIFE 104 HOURS for adults

With the longest half-life of any FIX therapy at 104 hours on a single dose,* factor levels remain high enough to extend protection. Some adults can go up to 2 weeks between doses—while keeping factor levels high to keep them protected.

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What is half-life?

Half-life measures how long it takes for the activity level of your infused factor to drop by 50%. A longer half-life means that the drug is present in your body for a longer time.

*Based on a single dose of IDELVION at 50 IU/kg in adults (≥18 years).

†Once well controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.

IDELVION is designed with albumin to keep FIX in your body longer until needed to control bleeds.

Recombinant albumin is an important
component of IDELVION. Albumin, a
protein that can be found naturally in your
body, is known for its long half-life.

When a bleed occurs, the linker
connecting recombinant albumin and
rFIX in IDELVION is separated, activating
the rFIX to stop the bleeding.

Recombinant Factor IX (rFIX)
is linked to the recombinant
albumin and remains active until
it’s needed to control a bleed.

MOA molecule – Recombinant albumin
  • 1

    Recombinant albumin is an important component of IDELVION. Albumin, a protein that can be found naturally in your body, is known for its long half-life.

  • 2

    When a bleed occurs, the linker connecting recombinant albumin and rFIX in IDELVION is separated, activating the rFIX to stop the bleeding.

  • 3

    Recombinant Factor IX (rFIX) is linked to the recombinant albumin and remains active until it’s needed to control a bleed.

Why Tony chose IDELVION

What interested me about IDELVION was that it used albumin. From studying biology I knew it was a naturally occurring protein in the body.

SEE MORE REAL-LIFE STORIES

UP TO 14 DAY DOSING FDA APPROVED

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