Mechanic—Extends protection. Extended time between doses. Half-life 104 hours for adults.

How It Works YOUR FACTOR IX
SHOULD
WORK AS
HARD AS
YOU DO

Extended protection.
Extended time
between doses.

With the longest single-dose half-life of any FIX therapy at 104 hours,* you don’t need to stop the action to infuse as often. You can keep your factor levels high. Some adults can go up to 2 weeks between doses with high factor levels.

HALF-LIFE 104 HOURS for adults
Question Mark

What is half-life?

Half-life measures how long it takes for the activity level of your infused factor to drop by 50%. A longer half-life means that the drug is present in your body for a longer time.

*Based on a single dose of IDELVION at 50 IU/kg in adults (≥18 years).

Once well-controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.

With IDELVION, Factor IX stays in your body longer

Recombinant albumin is an important
component of IDELVION. Albumin, a
protein that can be found naturally in your
body, is known for its long half-life.

When a bleed occurs, the linker
connecting recombinant albumin and
rFIX in IDELVION is separated, activating
the rFIX to stop the bleeding.

Recombinant Factor IX (rFIX)
is linked to the recombinant
albumin and remains active until
it’s needed to control a bleed.

MOA molecule – Recombinant albumin
  • 1

    Recombinant albumin is an important component of IDELVION. Albumin, a protein that can be found naturally in your body, is known for its long half-life.

  • 2

    When a bleed occurs, the linker connecting recombinant albumin and rFIX in IDELVION is separated, activating the rFIX to stop the bleeding.

  • 3

    Recombinant Factor IX (rFIX) is linked to the recombinant albumin and remains active until it’s needed to control a bleed.

Why Tony chose IDELVION

What interested me about IDELVION was that it used albumin. From studying biology I knew it was a naturally occurring protein in the body.

SEE MORE REAL-LIFE STORIES

Talk to other people living with hemophilia B

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Bleed protection with less frequent infusions

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