Powerful Prophylaxis

LIFE IS TOO
GOOD TO
MISS OUT
BECAUSE
OF A BLEED

IDELVION offers powerful bleed protection for all ages

ADULT AND ADOLESCENT DATA (≥12)
PEDIATRIC DATA (<12)

Starts strong and lasts long

IDELVION starts strong and lasts long with the longest single-dose half-life of any FIX, maintaining 20% trough levels on 7-day prophylaxis for adults and adolescents.*

20% trough fix levels on 7-day dosing
longest single dose half life

Based on a single dose of IDELVION at 50 IU/kg in adults (≥ 18 years).

*The average dose for adults and adolescents receiving prophylaxis every 7 days was 37 IU/kg.

High trough levels and a long half-life means Factor IX stays in your body longer.

What are trough levels?

Trough levels are when your FIX levels are at their lowest before your next injection. Since bleeds are more likely to happen at low trough levels, the higher yours are, the better protected you are from bleeds.

trough level graph

What does half-life mean?

Half-life is the amount of time for levels to decrease by half after infusion. The longer the half-life, the longer Factor IX stays in your body.

half-life graph
SEE THE SCIENCE BEHIND HOW IDELVION WORKS

Reclaim spontaneous

High factor levels and a longer half-life on prophylaxis means powerful bleed protection. For 7-day and 14-day dosing, people on IDELVION showed a median of zero spontaneous and joint bleeds in pivotal trials.

zero spontaneous bleeds
zero joint bleeds

The median AsBR for people who started and stayed on 7- or 14-day prophylaxis was 0. For people who switched to prophylaxis from on-demand, the median AsBR was 0.7. AsBR=annualized spontaneous bleed rate.

SEE INFORMATION FOR CAREGIVERS HERE

Children deserve to dream big

IDELVION starts strong and lasts long with the longest single-dose half life of any FIX, maintaining 13% trough levels on 7-day prophylaxis for patients under 12.*

13% trough fix levels on 7-day dosing
longest single dose half life

Based on a single dose of IDELVION at 50 IU/kg in children (< 12 years).

*The average dose for children receiving prophylaxis every 7 days was 47 IU/kg.

High trough levels and a long half-life means Factor IX stays in your body longer.

What are trough levels?

Trough levels are when your FIX levels are at their lowest before your next injection. Since bleeds are more likely to happen at low trough levels, the higher yours are, the better protected you are from bleeds.

graph showing trough levels over weeks

What does half-life mean?

Half-life is the amount of time for levels to decrease by half after infusion. The longer the half-life, the longer Factor IX stays in your body.

graph showing trough half life over time
SEE THE SCIENCE BEHIND HOW IDELVION WORKS

Reclaim spontaneous

High factor levels and a longer half-life on prophylaxis means powerful bleed protection. In pivotal trials, pediatric patients on IDELVION showed an average of zero spontaneous bleeds and less than one joint bleed on 7-day dosing.

zero spontaneous bleeds
less than one joint bleeds

The median annualized spontaneous bleeding rate was 0 on 7-day dosing.
The median annualized joint bleeding rate was 0.99 on 7-day dosing.

GET MORE INFORMATION FOR CAREGIVERS HERE
Doctor Discussion Guide

Use our guide to start the conversation with your healthcare provider to see if IDELVION is right for you

Doctor Discussion Guide

Fit dosing to your schedule, not the other way around

104-hour single-dose half-life means extended bleed protection. You can stay at 7-day or, if you're well-controlled, infuse less often—IDELVION is the only FDA-approved FIX for 14-day dosing. Choose the frequency of dosing with your doctor that works best with the lifestyle you want.

Zipliner—Start and stay on 7-day dosing

‡Once well-controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.

Zipliner—Start and stay on 7-day dosing

IDELVION keeps up with them

High factor levels offer powerful bleed protection at the very start. After turning 12, patients may be able to work with their doctor to extend dosing and infuse less—only IDELVION is FDA approved for 14-day dosing in adolescents and adults.

Zipliner—Start and stay on 7-day dosing.

§Once well‑controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.

Zipliner—Start and stay on 7-day dosing

Explore IDELVION dosing options

dosing icon

As a caregiver, you play a vital role in treatment, and we have information just for you

Milinda–Patient testimonial

Real people sharing their experiences with IDELVION

thumbnail of patient Michael
X
You are now leaving the current website.

Do you want to continue?