POWERFUL BLEED PROTECTION IN PROPHYLAXIS

hero-powerful-bleed-protection-in-prophylaxis

IDELVION delivers powerful protection

When dosed every 7 or 14 days, IDELVION had a zero median annualized spontaneous and joint bleeding rate.

When dosed at 7 days, IDELVION had an interquartile range, or IQR, of 0 to 0 spontaneous and joint bleeds (IQR at 14 days was 0 to 1 for spontaneous bleeds and 0 to 1.04 for joint bleeds). IQR looks at the middle 50% of people in a clinical study.

Zero spontaneous bleeds

John on the bleed protection IDELVION gives him



“It’s the peace of mind I get having higher factor levels.”

SEE MORE REAL-LIFE STORIES

Extends time between infusions

IDELVION is the only FDA-approved Factor IX therapy that lets some people go up to two weeks between doses—while still maintaining high factor levels and prolonged bleed protection. Explore what 14-day* dosing with IDELVION can do.

*Once well controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.

Up to 14-DAY DOSING

Takes Factor IX to another level in prophylaxis

IDELVION delivered high and sustained factor trough levels—20% with prophylactic use at steady state when dosed every 7 days.

  • 13% steady-state trough levels were achieved at 14-day dosing
  • Children younger than 12 years old achieved 13% steady-state trough levels on 7-day dosing§

†Steady state is a consistent and uniform amount of factor in the body from continued use.

‡The average dose for people receiving prophylaxis every 7 days was 37 IU/kg and every 14 days was 73 IU/kg.

§The average dose for children receiving prophylaxis every 7 days was 47 IU/kg.

STEADY-STATE TROUGH LEVELS 21% 7-DAY, 13% 14-DAY WITH PROPHYLACTIC USE
Question mark

What are factor trough levels?

Trough levels are the low point factor levels reach shortly before a new dose. Having high factor levels even at the lowest point between doses means you’re better protected even when you’re most vulnerable.

Doctor Discussion Guide

Use our guide to spark a conversation with your doctor

DOWNLOAD GUIDE

Recombinant IX fusion protein

IDELVION extends half-life using
albumin fusion technology

John – patient testimonial

Real people sharing their
experiences with IDELVION

X
You are now leaving the current website.

Do you want to continue?