IDELVION offers powerful bleed protection for all ages
Starts strong and lasts long
IDELVION starts strong and lasts long with the longest single-dose half-life of any FIX, maintaining 20% trough levels on 7-day prophylaxis for adults and adolescents.*
Based on a single dose of IDELVION at 50 IU/kg in adults (≥ 18 years).
*The average dose for adults and adolescents receiving prophylaxis every 7 days was 37 IU/kg.
High trough levels and a long half-life means Factor IX stays in your body longer.
What are trough levels?
Trough levels are when your FIX levels are at their lowest before your next injection. Since bleeds are more likely to happen at low trough levels, the higher yours are, the better protected you are from bleeds.
What does half-life mean?
Half-life is the amount of time for levels to decrease by half after infusion. The longer the half-life, the longer Factor IX stays in your body.
Reclaim spontaneous
High factor levels and a longer half-life on prophylaxis means powerful bleed protection. For 7-day and 14-day dosing, people on IDELVION showed a median of zero spontaneous and joint bleeds in pivotal trials.
†The median AsBR for people who started and stayed on 7- or 14-day prophylaxis was 0. For people who switched to prophylaxis from on-demand, the median AsBR was 0.7. AsBR=annualized spontaneous bleed rate.
Children deserve to dream big
IDELVION starts strong and lasts long with the longest single-dose half life of any FIX, maintaining 13% trough levels on 7-day prophylaxis for patients under 12.*
Based on a single dose of IDELVION at 50 IU/kg in children (< 12 years).
*The average dose for children receiving prophylaxis every 7 days was 47 IU/kg.
High trough levels and a long half-life means Factor IX stays in your body longer.
What are trough levels?
Trough levels are when your FIX levels are at their lowest before your next injection. Since bleeds are more likely to happen at low trough levels, the higher yours are, the better protected you are from bleeds.
What does half-life mean?
Half-life is the amount of time for levels to decrease by half after infusion. The longer the half-life, the longer Factor IX stays in your body.
Reclaim spontaneous
High factor levels and a longer half-life on prophylaxis means powerful bleed protection. In pivotal trials, pediatric patients on IDELVION showed an average of zero spontaneous bleeds and less than one joint bleed on 7-day dosing.
†The median annualized spontaneous bleeding rate was 0 on 7-day dosing.
‡The median annualized joint bleeding rate was 0.99 on 7-day dosing.
Use our guide to start the conversation with your healthcare provider to see if IDELVION is right for you
Fit dosing to your schedule, not the other way around
104-hour single-dose half-life means extended bleed protection. You can stay at 7-day or, if you're well-controlled, infuse less often—IDELVION is the only FDA-approved FIX for 14-day dosing. Choose the frequency of dosing with your doctor that works best with the lifestyle you want.
‡Once well-controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.
IDELVION keeps up with them
High factor levels offer powerful bleed protection at the very start. After turning 12, patients may be able to work with their doctor to extend dosing and infuse less—only IDELVION is FDA approved for 14-day dosing in adolescents and adults.
§Once well‑controlled (1 month without spontaneous bleeding or requiring dose adjustments on a weekly dose of ≤40 IU/kg), people 12 years and older can be transitioned to 14-day dosing.
Explore IDELVION dosing options
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